Abstract
AbstractThe large size of imaging datasets generated by
next-generation histology methods limits the adoption of those
approaches in research and the clinic. We propose pAPRica
(pipelines for Adaptive Particle Representation image compositing
and analysis), a framework based on the Adaptive Particle
Representation (APR) to enable efficient analysis of large
microscopy datasets, scalable up to petascale on a regular
workstation. pAPRica includes stitching, merging, segmentation,
registration, and mapping to an atlas as well as visualization of
the large 3D image data, achieving 100+ fold speedup in
computation and commensurate data-size reduction.
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