%0 Journal Article %1 901e3f89aab84244a9b9c1a17b6efd57 %A Al-Fatlawi, Ali %A Schroeder, Michael %A Stewart, A Francis %D 2023 %I Springer Nature %J Communications biology %K topic_lifescience DNA FIS_scads Homologous Protein/genetics Rad52 Recombination Recombination, Repair and %N 1 %R 10.1038/s42003-023-04476-z %T The Rad52 SSAP superfamily and new insight into homologous recombination %V 6 %X Rad52 is a highly conserved eukaryotic protein that can mediate the annealing of complementary DNA strands to initiate homologous recombination for the repair of double-strand breaks. Suspicions that at least some prokaryotic single-strand annealing proteins (SSAPs) are related to Rad52 have been discussed for more than two decades. Two recent cryo-EM structures, now put the issue beyond doubt.

@article{901e3f89aab84244a9b9c1a17b6efd57, abstract = {Rad52 is a highly conserved eukaryotic protein that can mediate the annealing of complementary DNA strands to initiate homologous recombination for the repair of double-strand breaks. Suspicions that at least some prokaryotic single-strand annealing proteins (SSAPs) are related to Rad52 have been discussed for more than two decades. Two recent cryo-EM structures, now put the issue beyond doubt.}, added-at = {2024-11-28T16:27:18.000+0100}, author = {Al-Fatlawi, Ali and Schroeder, Michael and Stewart, {A Francis}}, biburl = {https://puma.scadsai.uni-leipzig.de/bibtex/22b602c0cd620e34a22c4039ee381906c/scadsfct}, day = 23, doi = {10.1038/s42003-023-04476-z}, interhash = {109730739f5c570eb25a9e4af540c636}, intrahash = {2b602c0cd620e34a22c4039ee381906c}, issn = {2399-3642}, journal = {Communications biology}, keywords = {topic_lifescience DNA FIS_scads Homologous Protein/genetics Rad52 Recombination Recombination, Repair and}, language = {English}, month = jan, note = {Funding Information: We gratefully acknowledge support from ZIH of TU Dresden and the BMBF Project scads.ai.}, number = 1, publisher = {Springer Nature}, timestamp = {2024-11-28T17:41:30.000+0100}, title = {The Rad52 SSAP superfamily and new insight into homologous recombination}, volume = 6, year = 2023 }