Abstract
Abstract Chemistry is engaged with a subject that is not static
but evolving in time, in chemical space, namely, the collection
of all substances and reactions reported over time. If we accept
that premise, we can identify the path dependencies and
self-reinforcing mechanisms that determined its current space
and selected it across historical alternatives. In particular,
data analysis allows us to identify two crucial turning points.
One was the introduction of structural theory in 1860, the other
a technological shift around 1980.
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