OBJECTIVE: Sierra Platinum is a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering. The required computing resources are optimized but still may exceed the resources available to researchers at biological research institutes. RESULTS: Sierra Platinum Service provides the full functionality of Sierra Platinum: using a web interface, a new instance of the service can be generated. Then experimental data is uploaded and the computation of the peaks is started. Upon completion, the results can be inspected interactively and then downloaded for further analysis, at which point the service terminates.
%0 Journal Article
%1 Wiegreffe2018-qa
%A Wiegreffe, Daniel
%A Müller, Lydia
%A Steuck, Jens
%A Zeckzer, Dirk
%A Stadler, Peter F
%D 2018
%J BMC Res. Notes
%K ChIP-seq; Histone Peak-caller; Replicate analysis modifications;
%N 1
%P 512
%T The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
%V 11
%X OBJECTIVE: Sierra Platinum is a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering. The required computing resources are optimized but still may exceed the resources available to researchers at biological research institutes. RESULTS: Sierra Platinum Service provides the full functionality of Sierra Platinum: using a web interface, a new instance of the service can be generated. Then experimental data is uploaded and the computation of the peaks is started. Upon completion, the results can be inspected interactively and then downloaded for further analysis, at which point the service terminates.
@article{Wiegreffe2018-qa,
abstract = {OBJECTIVE: Sierra Platinum is a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering. The required computing resources are optimized but still may exceed the resources available to researchers at biological research institutes. RESULTS: Sierra Platinum Service provides the full functionality of Sierra Platinum: using a web interface, a new instance of the service can be generated. Then experimental data is uploaded and the computation of the peaks is started. Upon completion, the results can be inspected interactively and then downloaded for further analysis, at which point the service terminates.},
added-at = {2024-09-10T11:54:51.000+0200},
author = {Wiegreffe, Daniel and M{\"u}ller, Lydia and Steuck, Jens and Zeckzer, Dirk and Stadler, Peter F},
biburl = {https://puma.scadsai.uni-leipzig.de/bibtex/2d909d4a14074edc366595327d8745c9a/scadsfct},
interhash = {4a6d217016c10c6c94ce7d5acf21e3b5},
intrahash = {d909d4a14074edc366595327d8745c9a},
journal = {BMC Res. Notes},
keywords = {ChIP-seq; Histone Peak-caller; Replicate analysis modifications;},
language = {en},
month = jul,
number = 1,
pages = 512,
timestamp = {2024-09-10T11:54:51.000+0200},
title = {The Sierra Platinum Service for generating peak-calls for replicated {ChIP-seq} experiments},
volume = 11,
year = 2018
}
