%0 Unpublished Work %1 Oliveira_Monteiro2021-ua %A Oliveira Monteiro, Lummy Maria %A Saraiva, Joao %A Toscan, Rodolfo Brizola %A Stadler, Peter F %A Silva-Rocha, Rafael %A da Rocha, Ulisses Nunes %D 2021 %J bioRxiv %K %T PredicTF: a tool to predict bacterial transcription factors in complex microbial communities %X AbstractTranscription Factors (TFs) are proteins that control the flow of genetic information by regulating cellular gene expression. Here we describe PredicTF, a first platform supporting the prediction and classification of novel bacterial TF in complex microbial communities. We evaluated PredicTF using a two-step approach. First, we tested PredictTF's ability to predict TFs for the genome of an environmental isolate. In the second evaluation step, PredicTF was used to predict TFs in a metagenome and 11 metatranscriptomes recovered from a community performing anaerobic ammonium oxidation (anammox) in a bioreactor. PredicTF is open source pipeline available at https://github.com/mdsufz/PredicTF.

@unpublished{Oliveira_Monteiro2021-ua, abstract = {AbstractTranscription Factors (TFs) are proteins that control the flow of genetic information by regulating cellular gene expression. Here we describe PredicTF, a first platform supporting the prediction and classification of novel bacterial TF in complex microbial communities. We evaluated PredicTF using a two-step approach. First, we tested PredictTF's ability to predict TFs for the genome of an environmental isolate. In the second evaluation step, PredicTF was used to predict TFs in a metagenome and 11 metatranscriptomes recovered from a community performing anaerobic ammonium oxidation (anammox) in a bioreactor. PredicTF is open source pipeline available at https://github.com/mdsufz/PredicTF.}, added-at = {2024-09-10T11:56:37.000+0200}, author = {Oliveira Monteiro, Lummy Maria and Saraiva, Joao and Toscan, Rodolfo Brizola and Stadler, Peter F and Silva-Rocha, Rafael and da Rocha, Ulisses Nunes}, biburl = {https://puma.scadsai.uni-leipzig.de/bibtex/2fac3b21b235d1fe6cb1dbccd1beb6032/scadsfct}, institution = {bioRxiv}, interhash = {b62a4bd2c2985bb29013a8019715a152}, intrahash = {fac3b21b235d1fe6cb1dbccd1beb6032}, journal = {bioRxiv}, keywords = {}, month = jan, timestamp = {2024-09-10T15:15:57.000+0200}, title = {{PredicTF}: a tool to predict bacterial transcription factors in complex microbial communities}, year = 2021 }