Interpretable Chirality-Aware Graph Neural Network for Quantitative Structure Activity Relationship Modeling in Drug Discovery. Proceedings of the AAAI Conference on Artificial Intelligence, (37)12:14356â14364, Association for the Advancement of Artificial Intelligence (AAAI), June 2023. [PUMA: imported topic_lifescience] URL
Modeling conformational states of proteins with AlphaFold. Current Opinion in Structural Biology, (81):102645, Elsevier BV, August 2023. [PUMA: imported topic_lifescience] URL
Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants. Cold Spring Harbor Laboratory, October 2023. [PUMA: imported topic_lifescience] URL
Combining machine learning with structure-based protein design to predict and engineer post-translational modifications of proteins. In Joanna Slusky (Eds.), PLOS Computational Biology, (20)3:e1011939, Public Library of Science (PLoS), March 2024. [PUMA: imported topic_lifescience] URL
Self-supervised machine learning methods for protein design improve sampling, but not the identification of high-fitness variants. Cold Spring Harbor Laboratory, June 2024. [PUMA: imported topic_lifescience] URL
Template-free prediction of a new monotopic membrane protein fold and oligomeric assembly by Alphafold2. Cold Spring Harbor Laboratory, July 2022. [PUMA: imported topic_lifescience] URL
Sampling alternative conformational states of transporters and receptors with AlphaFold2. eLife, (11)eLife Sciences Publications, Ltd, March 2022. [PUMA: imported topic_lifescience] URL
A Multitask Deep-Learning Method for Predicting Membrane Associations and Secondary Structures of Proteins. Journal of Proteome Research, (20)8:4089â4100, American Chemical Society (ACS), July 2021. [PUMA: imported topic_lifescience] URL
Autocorrelation descriptor improvements for QSAR: 2DA_Sign and 3DA_Sign. Journal of Computer-Aided Molecular Design, (30)3:209â217, Springer Science and Business Media LLC, December 2015. [PUMA: imported topic_lifescience] URL
Strandâloopâstrand motifs: Prediction of hairpins and diverging turns in proteins. Proteins: Structure, Function, and Bioinformatics, (54)2:282â288, Wiley, December 2003. [PUMA: imported topic_lifescience] URL
Towards Generalizable Predictions for the Effects of Mutations on G-Protein Coupled Receptor Expression. Cold Spring Harbor Laboratory, December 2021. [PUMA: imported topic_lifescience] URL
Advancements in Ligand-Based Virtual Screening through the Synergistic Integration of Graph Neural Networks and Expert-Crafted Descriptors. Cold Spring Harbor Laboratory, April 2023. [PUMA: imported topic_lifescience] URL
Using Neural Networks for 13C NMR Chemical Shift PredictionâComparison with Traditional Methods. Journal of Magnetic Resonance, (157)2:242â252, Elsevier BV, August 2002. [PUMA: imported topic_lifescience] URL
3D Deep Learning for Biological Function Prediction from Physical Fields. 2020 International Conference on 3D Vision (3DV), 928â937, IEEE, November 2020. [PUMA: imported topic_lifescience] URL
Computational Methods in Drug Discovery. In Eric L. Barker (Eds.), Pharmacological Reviews, (66)1:334â395, American Society for Pharmacology & Experimental Therapeutics (ASPET), December 2013. [PUMA: imported topic_lifescience] URL
BCL::EMAS â Enantioselective Molecular Asymmetry Descriptor for 3D-QSAR. Molecules, (17)8:9971â9989, MDPI AG, August 2012. [PUMA: imported topic_lifescience] URL
Benchmarking Peptide Structure Prediction with AlphaFold2. Cold Spring Harbor Laboratory, February 2022. [PUMA: imported topic_lifescience] URL
Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA0201. Cold Spring Harbor Laboratory, November 2024. [PUMA: imported topic_lifescience] URL
Introduction to the BioChemical Library (BCL): An Application-Based Open-Source Toolkit for Integrated Cheminformatics and Machine Learning in Computer-Aided Drug Discovery. Frontiers in Pharmacology, (13)Frontiers Media SA, February 2022. [PUMA: imported topic_lifescience] URL
A Novel Method for Guiding Protein-Ligand Docking with QSAR-Derived Pharmacophore Maps. Biophysical Journal, (100)3:394aâ395a, Elsevier BV, February 2011. [PUMA: imported topic_lifescience] URL
Predicting the Functional Impact of KCNQ1 Variants with Artificial Neural Networks. Cold Spring Harbor Laboratory, December 2021. [PUMA: imported topic_lifescience] URL
Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants. In Jeffrey L Brodsky (Eds.), PLOS ONE, (19)1:e0297560, Public Library of Science (PLoS), January 2024. [PUMA: imported topic_lifescience] URL
Computational epitope mapping of class I fusion proteins using low complexity supervised learning methods. In Dina Schneidman (Eds.), PLOS Computational Biology, (18)12:e1010230, Public Library of Science (PLoS), December 2022. [PUMA: imported topic_lifescience] URL
Deep Learning for Virtual Screening: Five Reasons to Use ROC Cost Functions. arXiv, 2020. [PUMA: imported topic_lifescience] URL
SuperWater: Predicting Water Molecule Positions on Protein Structures by Generative AI. Cold Spring Harbor Laboratory, November 2024. [PUMA: imported topic_lifescience] URL
Quantitative StructureâActivity Relationship Modeling of Kinase Selectivity Profiles. Molecules, (22)9:1576, MDPI AG, September 2017. [PUMA: imported topic_lifescience] URL
Automated Structure Elucidation of Organic Molecules from 13C NMR Spectra Using Genetic Algorithms and Neural Networks. Journal of Chemical Information and Computer Sciences, (41)6:1535â1546, American Chemical Society (ACS), October 2001. [PUMA: imported topic_lifescience] URL
An Active Learning Framework Improves Tumor Variant Interpretation. Cancer Research, (82)15:2704â2715, American Association for Cancer Research (AACR), June 2022. [PUMA: imported topic_lifescience] URL
Heterogeneity of the GFP fitness landscape and data-driven protein design. Cold Spring Harbor Laboratory, December 2021. [PUMA: imported topic_lifescience] URL
Coupled prediction of protein secondary and tertiary structure. Proceedings of the National Academy of Sciences, (100)21:12105â12110, Proceedings of the National Academy of Sciences, October 2003. [PUMA: imported topic_lifescience] URL
Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes. Bioorganic & Medicinal Chemistry Letters, (26)18:4487â4491, Elsevier BV, September 2016. [PUMA: imported topic_lifescience] URL
Sampling the conformational landscapes of transporters and receptors with AlphaFold2. Cold Spring Harbor Laboratory, November 2021. [PUMA: imported topic_lifescience] URL
VUStruct: a compute pipeline for high throughput and personalized structural biology. Cold Spring Harbor Laboratory, August 2024. [PUMA: imported topic_lifescience] URL
Computer-Aided Design and Biological Evaluation of Diazaspirocyclic D4R Antagonists. ACS Chemical Neuroscience, (15)12:2396â2407, American Chemical Society (ACS), June 2024. [PUMA: imported topic_lifescience] URL
A unified hydrophobicity scale for multispan membrane proteins. Proteins: Structure, Function, and Bioinformatics, (76)1:13â29, Wiley, December 2008. [PUMA: imported topic_lifescience] URL
BCL::Mol2Dâa robust atom environment descriptor for QSAR modeling and lead optimization. Journal of Computer-Aided Molecular Design, (33)5:477â486, Springer Science and Business Media LLC, April 2019. [PUMA: imported topic_lifescience] URL
Neural Network Prediction of 13C NMR Chemical Shifts of Substituted Benzenes. Monatshefte für Chemie / Chemical Monthly, (130)9:1089â1095, Springer Science and Business Media LLC, September 1999. [PUMA: imported topic_lifescience] URL
Improving quantitative structureâactivity relationship models using Artificial Neural Networks trained with dropout. Journal of Computer-Aided Molecular Design, (30)2:177â189, Springer Science and Business Media LLC, February 2016. [PUMA: imported topic_lifescience] URL
3D-QSAR CoMFA study of benzoxazepine derivatives as mGluR5 positive allosteric modulators. Bioorganic & Medicinal Chemistry Letters, (20)19:5922â5924, Elsevier BV, October 2010. [PUMA: imported topic_lifescience] URL
Heterogeneity of the GFP fitness landscape and data-driven protein design. eLife, (11)eLife Sciences Publications, Ltd, May 2022. [PUMA: imported topic_lifescience] URL
General Purpose Structure-Based Drug Discovery Neural Network Score Functions with Human-Interpretable Pharmacophore Maps. Journal of Chemical Information and Modeling, (61)2:603â620, American Chemical Society (ACS), January 2021. [PUMA: imported topic_lifescience] URL
Application of machine learning approaches on quantitative structure activity relationships. 2009 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, 255â262, IEEE, March 2009. [PUMA: imported topic_lifescience] URL
GPU-accelerated machine learning techniques enable QSAR modeling of large HTS data. 2012 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 314â320, IEEE, May 2012. [PUMA: imported topic_lifescience] URL
Bcl∷ChemInfo - Qualitative analysis of machine learning models for activation of HSD involved in Alzheimerâs Disease. 2012 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 329â334, IEEE, May 2012. [PUMA: imported topic_lifescience] URL
Interpretable deep-learning pKa prediction for small molecule drugs via atomic sensitivity analysis. American Chemical Society (ACS), June 2024. [PUMA: imported topic_lifescience] URL
Fast Determination of 13C NMR Chemical Shifts Using Artificial Neural Networks. Journal of Chemical Information and Computer Sciences, (40)5:1169â1176, American Chemical Society (ACS), August 2000. [PUMA: imported topic_lifescience] URL
Predicting the functional impact of KCNQ1 variants with artificial neural networks. In Joanna Slusky (Eds.), PLOS Computational Biology, (18)4:e1010038, Public Library of Science (PLoS), April 2022. [PUMA: imported topic_lifescience] URL
Epothilones: Quantitative Structure Activity Relations Studied by Support Vector Machines and Artificial Neural Networks. QSAR & Combinatorial Science, (22)7:722â728, Wiley, October 2003. [PUMA: imported topic_lifescience] URL
Divergent Pairwise Epistasis in the Context of Unstable Membrane Protein Variants. eLife Sciences Publications, Ltd, December 2023. [PUMA: imported topic_lifescience] URL
Template-free prediction of a new monotopic membrane protein fold and assembly by AlphaFold2. Biophysical Journal, (122)11:2041â2052, Elsevier BV, June 2023. [PUMA: imported topic_lifescience] URL
Benchmarking Ligand-Based Virtual High-Throughput Screening with the PubChem Database. Molecules, (18)1:735â756, MDPI AG, January 2013. [PUMA: imported topic_lifescience] URL
Novel methods of automated structure elucidation based on 13C NMR spectroscopy. Magnetic Resonance in Chemistry, (42)12:1042â1045, Wiley, October 2004. [PUMA: imported topic_lifescience] URL
Approximating Projections of Conformational Boltzmann Distributions with AlphaFold2 Predictions: Opportunities and Limitations. Journal of Chemical Theory and Computation, (20)3:1434â1447, American Chemical Society (ACS), January 2024. [PUMA: imported topic_lifescience] URL
Biasing AlphaFold2 to predict GPCRs and kinases with user-defined functional or structural properties. Frontiers in Molecular Biosciences, (10)Frontiers Media SA, February 2023. [PUMA: imported topic_lifescience] URL
Approximating conformational Boltzmann distributions with AlphaFold2 predictions. Cold Spring Harbor Laboratory, August 2023. [PUMA: imported topic_lifescience] URL
Improved prediction of trans-membrane spans in proteins using an artificial neural network. 2009 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, 68â74, IEEE, March 2009. [PUMA: imported topic_lifescience] URL
Comparative analysis of machine learning techniques for the prediction of logP. 2011 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), 1â6, IEEE, April 2011. [PUMA: imported topic_lifescience] URL
Discovery of 2â(2âBenzoxazoyl amino)â4âArylâ5âCyanopyrimidine as Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptorâ 5 (mGlu5): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound. ChemMedChem, (7)3:406â414, Wiley, January 2012. [PUMA: imported topic_lifescience] URL
NetRank Recovers Known Cancer Hallmark Genes as Universal Biomarker Signature for Cancer Outcome Prediction. Frontiers in Bioinformatics, (2)Frontiers Media SA, March 2022. [PUMA: topic_lifescience imported] URL
Promiscuity in drug discovery on the verge of the structural revolution: recent advances and future chances. Expert Opinion on Drug Discovery, (18)9:973–985, Informa UK Limited, July 2023. [PUMA: topic_lifescience imported] URL
A genome-wide scan of wastewater E. coli for genes under positive selection: focusing on mechanisms of antibiotic resistance. Scientific Reports, (12)1Springer Science and Business Media LLC, May 2022. [PUMA: topic_lifescience imported] URL
Word-based GWAS harnesses the rich potential of genomic data for E. coli quinolone resistance. Frontiers in Microbiology, (14)Frontiers Media SA, December 2023. [PUMA: topic_lifescience imported] URL
A community effort in SARS‐CoV‐2 drug discovery. Molecular Informatics, (43)1Wiley, November 2023. [PUMA: topic_lifescience imported] URL
An interaction-based drug discovery screen explains known SARS-CoV-2 inhibitors and predicts new compound scaffolds. Scientific Reports, (13)1Springer Science and Business Media LLC, June 2023. [PUMA: topic_lifescience imported] URL
Decomposing compounds enables reconstruction of interaction fingerprints for structure-based drug screening. Journal of Cheminformatics, (14)1Springer Science and Business Media LLC, March 2022. [PUMA: topic_lifescience imported] URL
Targeting ion channels with ultra-large library screening for hit discovery. Frontiers in Molecular Neuroscience, (16)Frontiers Media SA, January 2024. [PUMA: topic_lifescience imported] URL
Ferric reduction by a CYBDOM protein counteracts increased iron availability in root meristems induced by phosphorus deficiency. Nature Communications, (15)1Springer Science and Business Media LLC, January 2024. [PUMA: topic_lifescience imported] URL
Similar Binding Modes of cGMP Analogues Limit Selectivity in Modulating Retinal CNG Channels via the Cyclic Nucleotide-Binding Domain. ACS Chemical Neuroscience, (15)8:1652–1668, American Chemical Society (ACS), April 2024. [PUMA: topic_lifescience imported] URL
Structural Studies on the Binding Mode of Bisphenols to PPARγ. Biomolecules, (14)6:640, MDPI AG, May 2024. [PUMA: topic_lifescience imported] URL
The First International Workshop on Open Web Search (WOWS). European Conference on Information Retrieval, 426--431, 2024. [PUMA: topic_language imported]
Impact and development of an Open Web Index for open web search. Journal of the Association for Information Science and Technology, (75)5:512--520, Wiley Online Library, 2024. [PUMA: topic_language imported]
Systematic Evaluation of Neural Retrieval Models on the Touché 2020 Argument Retrieval Subset of BEIR. Proceedings of the 47th International ACM SIGIR Conference on Research and Development in Information Retrieval, 1420–1430, ACM, July 2024. [PUMA: topic_language imported] URL
Report on the Dagstuhl Seminar on Frontiers of Information Access Experimentation for Research and Education. ACM SIGIR Forum, (57)1:1--28, 2023. [PUMA: topic_language imported]
The Information Retrieval Experiment Platform (Extended Abstract). Lernen. Wissen. Daten. Analysen. -- LWDA 2023, 179--191, CEUR-WS.org, October 2023. [PUMA: topic_language imported] URL
The Information Retrieval Experiment Platform (Extended Abstract). Proceedings of the Thirty-ThirdInternational Joint Conference on Artificial Intelligence, 8405–8410, International Joint Conferences on Artificial Intelligence Organization, August 2024. [PUMA: topic_language imported] URL
Prototyping Open Web Search Applications with TIRA: A Case Study in Research-oriented Teaching. In Andreas Wagner, Christian Guetl, Michael Granitzer, and Stefan Voigt (Eds.), 5th International Symposium on Open Search Technology (OSSYM 2023), International Open Search Symposium, October 2023. [PUMA: topic_language imported] URL
Open Web Search at LongEval 2023: Reciprocal Rank Fusion on Automatically Generated Query Variants. Sl: CEUR, 2023. [PUMA: topic_language imported]
Overview of Touché 2024: Argumentation Systems. 2024. [PUMA: topic_language imported]
Overview of PAN 2024: Multi-author Writing Style Analysis, Multilingual Text Detoxification, Oppositional Thinking Analysis, and Generative AI Authorship Verification Condensed Lab Overview. International Conference of the Cross-Language Evaluation Forum for European Languages, 231--259, 2024. [PUMA: topic_language imported]
Resources for Combining Teaching and Research in Information Retrieval Coursework. Proceedings of the 47th International ACM SIGIR Conference on Research and Development in Information Retrieval, 1115–1125, ACM, July 2024. [PUMA: topic_language imported] URL
The infinite index: Information retrieval on generative text-to-image models. Proceedings of the 2023 conference on human information interaction and retrieval, 172--186, 2023. [PUMA: topic_language imported]
Evaluating Generative Ad Hoc Information Retrieval. Proceedings of the 47th International ACM SIGIR Conference on Research and Development in Information Retrieval, 1916–1929, ACM, July 2024. [PUMA: topic_language imported] URL
Trigger Warnings: Bootstrapping a Violence Detector for Fan Fiction. Findings of the Association for Computational Linguistics: EMNLP 2023, 569–576, Association for Computational Linguistics, 2023. [PUMA: topic_language imported] URL
Small-Text: Active Learning for Text Classification in Python. In Danilo Croce, and Luca Soldaini (Eds.), Proceedings of the 17th Conference of the European Chapter of the Association for Computational Linguistics: System Demonstrations, 84--95, Association for Computational Linguistics, Dubrovnik, Croatia, May 2023. [PUMA: topic_language imported] URL
TL;DR Progress: Multi-faceted Literature Exploration in Text Summarization. In Nikolaos Aletras, and Orphee De Clercq (Eds.), Proceedings of the 18th Conference of the European Chapter of the Association for Computational Linguistics: System Demonstrations, 195--206, Association for Computational Linguistics, St. Julians, Malta, March 2024. [PUMA: topic_language imported] URL
Frame-oriented Summarization of Argumentative Discussions. Proceedings of the 24th Meeting of the Special Interest Group on Discourse and Dialogue, 114–129, Association for Computational Linguistics, 2023. [PUMA: topic_language imported] URL
Introducing Computational Research on Trigger Warnings. In Katrin Weller, Pascal Siegers, Indira Sen, and Christina Dahn (Eds.), Conference on Harmful Online Communication (CHOC 2023), Gesis, Cologne, Germany, November 2023. [PUMA: topic_language imported]
Beyond the Imitation Game: Quantifying and extrapolating the capabilities of language models. 2023. [PUMA: topic_language imported] URL
Overview of the Authorship Verification Task at PAN 2023. In Mohammad Aliannejadi, Guglielmo Faggioli, Nicola Ferro, and Michalis Vlachos (Eds.), Working Notes of the Conference and Labs of the Evaluation Forum (CLEF 2023), (3497):2476--2491, September 2023. [PUMA: topic_language imported] URL
Overview of the Multi-Author Writing Style Analysis Task at PAN 2023.. CLEF (Working Notes), 2513--2522, 2023. [PUMA: topic_language imported]
A large dataset of scientific text reuse in Open-Access publications. Scientific Data, (10)1:58, Nature Publishing Group UK London, 2023. [PUMA: topic_language imported]
GAIA Search: Hugging Face and Pyserini Interoperability for NLP Training Data Exploration. Proceedings of the 61st Annual Meeting of the Association for Computational Linguistics (Volume 3: System Demonstrations), 588–598, Association for Computational Linguistics, 2023. [PUMA: topic_language imported] URL
A New Dataset for Causality Identification in Argumentative Texts. Proceedings of the 24th Meeting of the Special Interest Group on Discourse and Dialogue, 349–354, Association for Computational Linguistics, 2023. [PUMA: topic_language imported] URL
Advertising in Generative Information Retrieval. Workshop on the Impact of Generative AI on Search and Search Engine Research, September 2023. [PUMA: topic_language imported]
Modeling Appropriate Language in Argumentation. Proceedings of the 61st Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers), 4344–4363, Association for Computational Linguistics, 2023. [PUMA: topic_language imported] URL
Generating Natural Language Queries for More Effective Systematic Review Screening Prioritisation. 2023. [PUMA: topic_language imported] URL
Commercialized Generative AI: A Critical Study of the Feasibility and Ethics of Generating Native Advertising Using Large Language Models in Conversational Web Search. 2023. [PUMA: topic_language imported] URL
Overview of the Trigger Detection Task at PAN 2023.. CLEF (Working Notes), 2523--2536, 2023. [PUMA: topic_language imported]
Citance-Contextualized Summarization of Scientific Papers. In Houda Bouamor, Juan Pino, and Kalika Bali (Eds.), Findings of the Association for Computational Linguistics: EMNLP 2023, 8551--8568, Association for Computational Linguistics, Singapore, December 2023. [PUMA: topic_language imported] URL
Indicative Summarization of Long Discussions. Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing, 2752–2788, Association for Computational Linguistics, 2023. [PUMA: topic_language imported] URL