Publications

Lorenzo Maiello, Lorenzo Ball, Marco Micali, Francesca Iannuzzi, Nico Scherf, Ralf-Thorsten Hoffmann, Marcelo Gama de Abreu, Paolo Pelosi, und Robert Huhle. Automatic lung segmentation and quantification of aeration in computed tomography of the chest using 3D transfer learning. Front. Physiol., (12):725865, 2021. [PUMA: ARDS; COVID-19; Jaccard deep index; learning; lung recruitment; segmentation; transfer uNet]

David Nam, Julius Chapiro, Valerie Paradis, Tobias Paul Seraphin, und Jakob Nikolas Kather. Artificial intelligence in liver diseases: Improving diagnostics, prognostics and response prediction. JHEP Rep., (4)4:100443, Elsevier BV, April 2022. [PUMA: AI, Artificial CNN, Communications DICOM, Diagnosis; Digital HCC, Imaging Individual ML, MVI, Medicine; NAFLD, NASH, Prognosis Reporting TACE, TRIPOD, Transparent WSIs, a and artificial carcinoma; chemoembolisation; convolutional data deep diagnostic disease; fatty for hepatocellular images; imaging; in integration intelligence; invasion; learning; liver machine microvascular model multimodal multivariable network; neural non-alcoholic of or prediction slide steatohepatitis; support system; transarterial whole]

Roman C Maron, Achim Hekler, Sarah Haggenmüller, Christof von Kalle, Jochen S Utikal, Verena Müller, Maria Gaiser, Friedegund Meier, Sarah Hobelsberger, Frank F Gellrich, Mildred Sergon, Axel Hauschild, Lars E French, Lucie Heinzerling, Justin G Schlager, Kamran Ghoreschi, Max Schlaak, Franz J Hilke, Gabriela Poch, Sören Korsing, Carola Berking, Markus V Heppt, Michael Erdmann, Sebastian Haferkamp, Dirk Schadendorf, Wiebke Sondermann, Matthias Goebeler, Bastian Schilling, Jakob N Kather, Stefan Fröhling, Daniel B Lipka, Eva Krieghoff-Henning, und Titus J Brinker. Model soups improve performance of dermoscopic skin cancer classifiers. Eur. J. Cancer, (173):307--316, Elsevier BV, September 2022. [PUMA: Artificial Calibration; Deep Dermatology; Ensembles; Generalisation; Melanoma; Model Nevus; Robustness intelligence; learning; soups; topic_lifescience]

Bian Li, Jeffrey Mendenhall, John A Capra, und Jens Meiler. A multitask deep-learning method for predicting membrane associations and secondary structures of proteins. J. Proteome Res., (20)8:4089--4100, American Chemical Society (ACS), August 2021. [PUMA: convolutional deep learning; long memory multitask networks; neural prediction prediction; secondary short-term structure topic_lifescience topology transmembrane]

Alexander Kurz, Katja Hauser, Hendrik Alexander Mehrtens, Eva Krieghoff-Henning, Achim Hekler, Jakob Nikolas Kather, Stefan Fröhling, Christof von Kalle, und Titus Josef Brinker. Uncertainty estimation in medical image classification: Systematic review. JMIR Med. Inform., (10)8:e36427, August 2022. [PUMA: calibration; classification; deep detection; estimation image imaging; learning; medical network out-of-distribution topic_lifescience uncertainty]

Narmin Ghaffari Laleh, Hannah Sophie Muti, Chiara Maria Lavinia Loeffler, Amelie Echle, Oliver Lester Saldanha, Faisal Mahmood, Ming Y Lu, Christian Trautwein, Rupert Langer, Bastian Dislich, Roman D Buelow, Heike Irmgard Grabsch, Hermann Brenner, Jenny Chang-Claude, Elizabeth Alwers, Titus J Brinker, Firas Khader, Daniel Truhn, Nadine T Gaisa, Peter Boor, Michael Hoffmeister, Volkmar Schulz, und Jakob Nikolas Kather. Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology. Med. Image Anal., (79)102474:102474, Elsevier BV, Juli 2022. [PUMA: Artificial Computational Convolutional Learning; Multiple-Instance Vision Weakly-supervised deep intelligence; learning networks; neural pathology; transformers;]

Chen Liu, Guillaume Bellec, Bernhard Vogginger, David Kappel, Johannes Partzsch, Felix Neumärker, Sebastian Höppner, Wolfgang Maass, Steve B Furber, Robert Legenstein, und Christian G Mayr. Memory-efficient deep learning on a SpiNNaker 2 prototype. Front. Neurosci., (12):840, Frontiers Media SA, November 2018. [PUMA: SpiNNaker; deep efficient energy footprint; hardware; memory parallelism; pruning; rewiring; sparsity]

Ali Al-Fatlawi, Negin Malekian, Sebastián Garc\'ıa, Andreas Henschel, Ilwook Kim, Andreas Dahl, Beatrix Jahnke, Peter Bailey, Sarah Naomi Bolz, Anna R Poetsch, Sandra Mahler, Robert Grützmann, Christian Pilarsky, und Michael Schroeder. Deep learning improves pancreatic cancer diagnosis using RNA-based variants. Cancers (Basel), (13)11:2654, MDPI AG, Mai 2021. [PUMA: association cancer; chronic deep learning; pancreatic pancreatitis; study topic_lifescience transcriptome-wide]

Chiara Maria Lavinia Loeffler, Nadina Ortiz Bruechle, Max Jung, Lancelot Seillier, Michael Rose, Narmin Ghaffari Laleh, Ruth Knuechel, Titus J Brinker, Christian Trautwein, Nadine T Gaisa, und Jakob N Kather. Artificial intelligence-based detection of FGFR3 mutational status directly from routine histology in bladder cancer: A possible preselection for molecular testing?. Eur. Urol. Focus, (8)2:472--479, Elsevier BV, März 2022. [PUMA: Artificial Bladder Deep FGFR3 Molecular cancer; factor fibroblast for growth intelligence; learning; mutations; receptor testing therapy]

Qinghe Zeng, Christophe Klein, Stefano Caruso, Pascale Maille, Narmin Ghaffari Laleh, Daniele Sommacale, Alexis Laurent, Giuliana Amaddeo, David Gentien, Audrey Rapinat, Hélène Regnault, Cécile Charpy, Cong Trung Nguyen, Christophe Tournigand, Raffaele Brustia, Jean Michel Pawlotsky, Jakob Nikolas Kather, Maria Chiara Maiuri, Nicolas Loménie, und Julien Calderaro. Artificial intelligence predicts immune and inflammatory gene signatures directly from hepatocellular carcinoma histology. J. Hepatol., (77)1:116--127, Elsevier BV, Juli 2022. [PUMA: artificial deep gene image immune intelligence; learning; pathology; signatures; slide whole]

Benjamin P Brown, Oanh Vu, Alexander R Geanes, Sandeepkumar Kothiwale, Mariusz Butkiewicz, Edward W Lowe, Jr, Ralf Mueller, Richard Pape, Jeffrey Mendenhall, und Jens Meiler. Introduction to the BioChemical Library (BCL): An application-based open-source toolkit for integrated cheminformatics and machine learning in computer-aided drug discovery. Front. Pharmacol., (13):833099, Frontiers Media SA, Februar 2022. [PUMA: BCL; QSAR; biochemical cheminformatics; deep design; discovery; drug library; network; neural open-source topic_lifescience]

Chiara Maria Lavinia Loeffler, Nadine T Gaisa, Hannah Sophie Muti, Marko van Treeck, Amelie Echle, Narmin Ghaffari Laleh, Christian Trautwein, Lara R Heij, Heike I Grabsch, Nadina Ortiz Bruechle, und Jakob Nikolas Kather. Predicting mutational status of driver and suppressor genes directly from histopathology with Deep Learning: A systematic study across 23 solid tumor types. Front. Genet., (12):806386, 2021. [PUMA: (AI); TCGA; artificail cancer deep genes; genetic intelligence learning; pathway pathway;]

Peter Leonard Schrammen, Narmin Ghaffari Laleh, Amelie Echle, Daniel Truhn, Volkmar Schulz, Titus J Brinker, Hermann Brenner, Jenny Chang-Claude, Elizabeth Alwers, Alexander Brobeil, Matthias Kloor, Lara R Heij, Dirk Jäger, Christian Trautwein, Heike I Grabsch, Philip Quirke, Nicholas P West, Michael Hoffmeister, und Jakob Nikolas Kather. Weakly supervised annotation-free cancer detection and prediction of genotype in routine histopathology. J. Pathol., (256)1:50--60, Wiley, Januar 2022. [PUMA: Lynch artificial cancer; colorectal computational deep digital instability intelligence; learning; microsatellite pathology; syndrome;]

Scarlet Brockmoeller, Amelie Echle, Narmin Ghaffari Laleh, Susanne Eiholm, Marie Louise Malmstrøm, Tine Plato Kuhlmann, Katarina Levic, Heike Irmgard Grabsch, Nicholas P West, Oliver Lester Saldanha, Katerina Kouvidi, Aurora Bono, Lara R Heij, Titus J Brinker, Ismayil Gögenür, Philip Quirke, und Jakob Nikolas Kather. Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer. J. Pathol., (256)3:269--281, Wiley, März 2022. [PUMA: AI; LNM adipose and artificial biomarker; bowel cancer; colorectal deep digital early inflamed intelligence; learning; metastasis; new pT1 pT2 pathology; prediction predictive tissue;]

Akshay Akshay, Mitali Katoch, Masoud Abedi, Navid Shekarchizadeh, Mustafa Besic, Fiona C Burkhard, Alex Bigger-Allen, Rosalyn M Adam, Katia Monastyrskaya, und Ali Hashemi Gheinani. SpheroScan: a user-friendly deep learning tool for spheroid image analysis. Gigascience, (12)Oxford University Press (OUP), Dezember 2022. [PUMA: 3D Image Mask R-CNN; analysis; deep high-throughput image learning; screening; segmentation spheroids;]

Daniel Bühler, Nicole Power Guerra, Luisa Müller, Olaf Wolkenhauer, Martin Düffer, Brigitte Vollmar, Angela Kuhla, und Markus Wolfien. Leptin deficiency-caused behavioral change - A comparative analysis using EthoVision and DeepLabCut. Front. Neurosci., (17):1052079, März 2023. [PUMA: DeepLabCut; EthoVision; analysis; behavioral deep learning; obesity]