Publications

Chiara Maria Lavinia Loeffler, Nadina Ortiz Bruechle, Max Jung, Lancelot Seillier, Michael Rose, Narmin Ghaffari Laleh, Ruth Knuechel, Titus J Brinker, Christian Trautwein, Nadine T Gaisa, and Jakob N Kather. Artificial intelligence-based detection of FGFR3 mutational status directly from routine histology in bladder cancer: A possible preselection for molecular testing?. Eur. Urol. Focus, (8)2:472--479, Elsevier BV, March 2022. [PUMA: Artificial intelligence; learning; therapy for Deep mutations; Bladder cancer; Molecular fibroblast receptor testing topic_lifescience growth factor FGFR3]

Davide Sala, Diego Del Alamo, Hassane S Mchaourab, and Jens Meiler. Modeling of protein conformational changes with Rosetta guided by limited experimental data. Structure, (30)8:1157--1168.e3, Elsevier BV, August 2022. [PUMA: molecular EPR dynamics; biology; integrative structure modeling; structural protein changes; topic_lifescience refinement conformational spectroscopy; Rosetta;]

Julia Scheel, Matti Hoch, Markus Wolfien, and Shailendra Gupta. NaviCenta - The disease map for placental research. Placenta, (143):12--15, Elsevier BV, November 2023. [PUMA: Networks biology Molecular integration; Omics topic_lifescience analysis; Systems interaction map;]

Souhrid Mukherjee, Thomas A. Cassini, Ningning Hu, Tao Yang, Bian Li, Wangzhen Shen, Christopher W. Moth, David C. Rinker, Jonathan H. Sheehan, Joy D. Cogan, John H. Newman, Rizwan Hamid, Robert L. Macdonald, Dan M. Roden, Jens Meiler, Georg Kuenze, John A. Phillips, and John A. Capra. Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by de novo KCNC2 variants. Human Genetics and Genomics Advances, (3)4:100131, 2022. [PUMA: developmental variant, disease molecular encephalopathy, electrophysiology, Diseases simulations, personalized structural rare dynamics interpretation, epileptic KCNC2, and topic_lifescience DEE, variant Network, Undiagnosed biology,] URL

Markus Kreuz, Dominik J Otto, Susanne Fuessel, Conny Blumert, Catharina Bertram, Sophie Bartsch, Dennis Loeffler, Sven-Holger Puppel, Michael Rade, Tilo Buschmann, Sabina Christ, Kati Erdmann, Maik Friedrich, Michael Froehner, Michael H Muders, Stephan Schreiber, Michael Specht, Marieta I Toma, Fabio Benigni, Massimo Freschi, Giorgio Gandaglia, Alberto Briganti, Gustavo B Baretton, Markus Loeffler, Jörg Hackermüller, Kristin Reiche, Manfred Wirth, and Friedemann Horn. ProstaTrend-A multivariable prognostic RNA expression score for aggressive prostate cancer. Eur. Urol., (78)3:452--459, Elsevier BV, September 2020. [PUMA: Biomarker; cancer; Next-generation Molecular pathology; testing; Transcriptome Personalized diagnostic medicine; Prostate sequencing;]

Alican Gulsevin, Andrew M Glazer, Tiffany Shields, Brett M Kroncke, Dan M Roden, and Jens Meiler. Veratridine can bind to a site at the mouth of the channel pore at human cardiac sodium channel NaV1.5. Int. J. Mol. Sci., (23)4:2225, MDPI AG, February 2022. [PUMA: toxins; mutagenesis; docking; molecular SCN5A; voltage-gated site-directed channels; channels sodium topic_lifescience veratridine; electrophysiology; cardiac Rosetta;]